�BIOTRONIK announced the enrolment of the first patient into the EchoCRT (Echocardiography guided Cardiac Resynchronization Therapy) study. Drs William T. Abraham and Ralph Augostini at The Ohio State University Medical Center in Columbus, Ohio, USA, enrolled and implanted the Lumax HF-T CRT-D device in the first patients in EchoCRT. This technologically in advance cardiac device has many industry-leading features to write and raise patients' lives and equipped with BIOTRONIK Home Monitoring� enables wireless, automatic everyday data transmission of patients' cardiovascular and device condition.
"The objective of EchoCRT is to demonstrate that optimal medical therapy asset CRT reduces all-cause mortality or first-class honours degree hospitalization for worsening center failure in the study population compared to optimum medical therapy alone" aforesaid Dr Johannes Holzmeister, University of Z�rich, Executive Committee Co-Chairman and International Co-Principal Investigator of EchoCRT. He added, "EchoCRT will provide valuable scientific evidence for this with child group of heart failure patients wHO currently want treatment options beyond pharmacologic therapy."
"Cardiac resynchronization is a proven life-saving device-based treatment for certain heart failure patients with ventricular dyssynchrony, that is, discoordinated pumping natural action of the heart," Dr Abraham, Director of the Division of Cardiovascular Medicine at The Ohio State University Medical Center and US Principal Investigator of the study, explained. "Previous randomized controlled trials with CRT own been modified to patients with a so-called 'wide QRS,' an electrocardiogram (ECG) anomaly that shows longer-than-normal ventricular action (QRS width ? 120 - 130 ms), who present only 30% of all subjects with chronic ticker failure. EchoCRT is designed to certify whether patients with ventricular dyssynchrony just 'narrow QRS' or normal ventricular electrical activity on the ECG, may derive the like life-saving benefits from CRT device therapy as former heart failure patients."
As the largest, prospective, randomized, double-blind, international, multicenter clinical trial of its kind, the landmark EchoCRT study will randomise more than 1,250 patients with heart failure, already receiving current touchstone pharmacological therapy, with a 'narrow QRS' width (
In recognition of its material clinical benefits, CRT has been recommended in both the European Society of Cardiology (ESC) Guidelines and in the American College of Cardiology (ACC)/American Heart Association (AHA) Guidelines for the diagnosis and treatment of chronic heart failure. However, these guidelines have limited the application of CRT to patients with a QRS width of ? 120 ms.1, 2 EchoCRT will assess whether some of the left 70% of heart failure patients with 'narrow QRS' could benefit from CRT therapy.
"The clinical community of interests has long been intrigued as to whether 'narrow-QRS' heart failure patients with ventricular dyssynchrony would benefit from CRT," stated Kevin Mitchell, BIOTRONIK Vice President Clinical Studies. "The EchoCRT study has been designed under steering from an executive steering committee of 11 internationally-renowned academic specialists in electrophysiology, heart failure and echocardiography who carefully considered before studies in developing the EchoCRT innovation. BIOTRONIK is proud to support this trial, which is part of our enduring committedness to landmark clinical enquiry, to cater physicians with scientifically-sound evidence on which to base their clinical decisions. BIOTRONIK is as well committed to improving affected role outcomes and to achieve this, the company has significantly expanded its clinical trial syllabus and has embarked on four orotund, international, landmark trials, including EchoCRT."
"Chronic heart failure is associated with a poor forecast with substantially shortened endurance and repeated hospitalizations. The vast legal age of patients with heart failure pose with a narrow QRS and do not presently receive CRT. The EchoCRT trial
Thursday 4 September 2008
Monday 25 August 2008
Fired Philly TV anchor admits e-mail hacking
PHILADELPHIA �
A laid-off TV newscaster admitted in court Friday that he illegally hacked into his co-anchor's email accounts and leaked private information around her to gossip columnists.
Larry Mendte admitted that he viewed hundreds of Alycia Lane's e-mails from March 2006 to May 2008, including ones from her agent, her then-husband and lawyers representing her after she was arrested in New York last year and fired from KYW-TV, Philadelphia's CBS affiliate.
"There is no question he wrecked her career," said attorney Paul Rosen, who represents Lane in her wrongful-termination suit against the station.
Mendte, 51, said at a news group discussion that his actions grew out of a feud with Lane, 36, that began after he complete what he said was a coquettish and unconventional relationship with her, including long dinners and late nights out together.
Rosen promptly disputed the account. He called Mendte "sick and narcissistic" and said there was never an inappropriate relationship.
Mendte, world Health Organization is married to local Fox news anchor Dawn Stensland, accused Lane of undermining his standing at the station after the relationship
Friday 15 August 2008
Radiohead, Jack Johnson Keep It Green At New Jersey's All Points West Festival
JERSEY CITY, New Jersey � The much-anticipated All Points West Music & Arts Festival kicked off in New Jersey's Liberty State Park this weekend with performances by Radiohead, Jack Johnson and the Kings of Leon, among others. But in addition to being the Tri-State area's number one weekend-long multi-band fest in quite some time, APW is besides hoping to make a name as the greenest festival around.
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Thursday 7 August 2008
Friday 27 June 2008
Grease - Grease Star Dead At 93
GREASE and GREASE 2 star DODY GOODMAN has died at a New Jersey hospital after a lengthy battle with illness. She was 93.
The beloved funnywoman, who was also a regular on late-night hit The Tonight Show in America in the 1950s and 1960s, played Principal MCGee's assistant Blanche in both Grease films.
Goodman was also a hit on Broadway, where she began her career after training as a dancer at the School of American Ballet and the Metropolitan Opera Ballet School in the late 1930s and early 1940s.
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Monday 23 June 2008
Sizzla, Journey: Very Best Of
Six years on from VP records' The Story Unfolds, the idiosyncratic and mercurial Bobo sing-jay Sizzla Kalonji is well overdue another retrospective. And this nicely-presented effort by VP's new acquisition, Greensleeves, including a bonus DVD, gives each chapter of the chronicle a fair hearing, even if the odd key verse has inevitably been missed out.
Sizzla's received a lot of flak for perceived changes to his voice. The reality is he's never stopped changing it. From aggressive shouting to wolf-like howls and high pitched feline wails, he's taken his now ravaged pipes in every possible direction, cutting astonishing tunes over some of Jamaica's most iconic rhythm tracks.
These range from the ruminative (Just One Of Those Days on Bobby Digital's relick of John Holt's Queen Majesty) to the uplifting (Good Ways using Digital's version of Alton Ellis' classic Studio 1 piece, Breaking Up) to the heavily prophetic (Africa Prepare on Frenchie's re-interpretation of Lee Perry's Blackboard Jungle). We also hear evidence of his more recent interest in hip hop and R&B with Give Me A Try and Rise To The Occasion (for Donovan Bennett aka Don Corleon).
Of course, an overview of such an important artist is bound to solicit some grumbles, the most trenchant being that not enough time is devoted to Sizzla's early work, which set the standard for sing-jaying in the 90s. What's more, his mellower side predominates: for a taste of the shouty Sizzla check the raw, camera mic recorded footage on the DVD. However, it's understandable that a best of, aimed at a wide audience, would avoid anything too uncompromising on the ear, although the odd smattering of homophobia is on display.
There are a few glaring omissions, particularly Solid As A Rock – both the cut from his Da Real Thing album, or his equally worthy Damon Dash-produced remake - but all in all, this is a good summary of a career that has constantly flouted convention and expectation. The Journey is a sometimes jarring mix of reflection, belligerence, political incorrectness and religious fervour - just like Sizzla himself.
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Monday 16 June 2008
Duffy - Fascinating Fact 5468
Soul singer DUFFY competed on the Welsh version of THE X FACTOR, WAWFFACTOR, in 2003.
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